If you are trying to minimize the effects of hair loss, cut your hair in short layers. Thinning hair looks best shorter and layered (since the style adds fullness and body).
If your hair is thinning, use soft brushes instead of combs and avoid hair spray. Use a good mousse or soft gel hair loss product after washing to give your hair additional body without harming it.
*It's best to alternate shampoos, switching at least once a month.